Project - Human Brain Connectivity with DSI Studio
I took a Human Brain Connectivity class during my last semester at the University of Pittsburgh where I was able to put my knowledge of the brain to the test. In this class, we thoroughly studied the facets of neural anatomy before delving into new technology - a tractography software tool called DSI Studio.
DSI Studio allows users to take brain MRI data and reconstruct entire brain tracts for neurostructural damage assessment. By accurately mapping fiber tracts, DSI Studio helps doctors find the safest, least invasive path for removing tumors.
Using the software, users are able to isolate specific tracts of the brain using ROI’s and ROA’s (Regions of Interest/Avoidance). Once isolated, a brain tract can be trimmed and compared with a healthy tract to diagnose overall health and functionality. Below is a timelapse of me going through this process to find the Uncinate Fasciculus.
To verify our findings, our class employed methods of machine learning such as linear regression, CART, and random forest models to determine brain tract health. We used R to create and run the models, as R is specifically built to do statistics programming. Employing such methods, I was able to create a model which predicts TBI (Traumatic Brain Injury) status for a group project.
Brain damage often goes unnoticed, leading to lasting issues like cognitive decline, emotional instability, and physical difficulties. Early detection and intervention are key to mitigating these effects and improving recovery. DSI Studio’s ability to provide detailed insights into brain structure plays a crucial role in these early detection efforts.
I'm grateful for the chance to apply advanced technology to practical, real-world applications in this course!
If you would like to know more about DSI studio and get the free software for yourself, check out their page at: DSI Studio